Name: DNAJC15抗原（重組蛋白）
Brand: 通蔚生物

中文名稱： DNAJC15抗原（重組蛋白）

英文名稱： DNAJC15 Antigen (Recombinant Protein)

別名： MCJ; HSD18; DNAJD1

儲存： 冷凍（-20℃）

相關(guān)類別： 抗原

概述：

Fusion protein corresponding to a region derived from 58-150 amino acids of human DNAJC15

技術(shù)規(guī)格：

Full name:	DnaJ (Hsp40) homolog, subfamily C, member 15
Synonyms:	MCJ; HSD18; DNAJD1
Swissprot:	Q9Y5T4
Gene Accession:	BC010910
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	The DnaJ family is one of the largest of all the chaperone families and has evolved with diverse cellular localization and functions. The presence of a J domain defines a protein as a member of the DnaJ family. DnaJ heat shock induced proteins are from the bacterium Escherichia coli and are under the control of the htpR regulatory protein. The DnaJ proteins play a critical role in the HSP 70 chaperone machine by interacting with HSP 70 to stimulate ATP hydrolysis. DnaJ proteins are important mediators of proteolysis and are involved in the regulation of protein degradation, exocytosis and endocytosis. MCJ (methylation-controlled J protein), also known as HSD18, DNAJD1 or DNAJC15, is a 150 amino acid ubiquitously expressed single-pass membrane protein containing one J domain. Localizing to the golgi apparatus and only present in vertebrates, MCJ may be associated with increased chemotherapeutic resistance in ovarian cancer by inducing expression of the Mdr drug transporter and preventing intracellular drug accumulation.

ELISA試劑盒

PCR試劑盒