中文名稱：GLP1R抗原（重組蛋白）

英文名稱：GLP1R Antigen (Recombinant Protein)

儲(chǔ) 存：冷凍（-20℃）

相關(guān)類(lèi)別：抗原

概述

Fusion protein corresponding to a region derived from 24-145 amino acids of human GLP1R

技術(shù)規(guī)格

Full name:

glucagon-like peptide 1 receptor

Swissprot:

P43220

Gene Accession:

BC113493

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The glucagon-like peptide 1 receptor (GLP1R) is a human gene which resides on chromosome 6.The protein encoded by this gene is a member of the glucagon receptor family of G protein-coupled receptors. GLP1R binds specifically the glucagon-like peptide-1 (GLP1) and has much lower affinity for related peptides such as the gastric inhibitory polypeptide and glucagon. GLP1R is known to be expressed in pancreatic beta cells. Activated GLP1R stimulates the adenylyl cyclase pathway which results in increased insulin synthesis and release of insulin. Consequently GLP1R has been suggested as a potential target for the treatment of diabetes.

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相關(guān)文章

GLP1R抗原（重組蛋白）

Full name:	glucagon-like peptide 1 receptor
Swissprot:	P43220
Gene Accession:	BC113493
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	The glucagon-like peptide 1 receptor (GLP1R) is a human gene which resides on chromosome 6.The protein encoded by this gene is a member of the glucagon receptor family of G protein-coupled receptors. GLP1R binds specifically the glucagon-like peptide-1 (GLP1) and has much lower affinity for related peptides such as the gastric inhibitory polypeptide and glucagon. GLP1R is known to be expressed in pancreatic beta cells. Activated GLP1R stimulates the adenylyl cyclase pathway which results in increased insulin synthesis and release of insulin. Consequently GLP1R has been suggested as a potential target for the treatment of diabetes.