購(gòu)物車(chē)
幫助
021-54845833/15800441009
中文名稱(chēng) : 小鼠抗FCMR單克隆抗體
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Background: |
May play a role in the immune system processes. Protects cells from FAS-, TNF alpha- and FADD-induced apoptosis without increasing expression of the inhibitors of apoptosis BCL2 and BCLXL. Seems to activate an inhibitory pathway that prevents CASP8 activation following FAS stimulation, rather than blocking apoptotic signals downstream. May inhibit FAS-induced apoptosis by preventing CASP8 processing through CFLAR up-regulation. |
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Applications: |
IHC |
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Name of antibody: |
FCMR |
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Immunogen: |
Fusion protein of human FCMR |
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Full name: |
Fc fragment of IgM receptor (FCMR), transcript variant 1 |
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Synonyms: |
TOSO; FAIM3 |
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SwissProt: |
O60667 |
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IHC positive control: |
carcinoma of human thyroid tissue |
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IHC Recommend dilution: |
30-150 |
